代慧，教授,博士生导师，入选国家高层次青年人才计划（海外）。2018年12月博士毕业于中国科学技术大学，2019-2024年在美国加利福尼亚大学河滨分校(UCR)进行博士后研究，2025年在香港城市大学担任Research Fellow工作，2026年1月加入买球的app排行榜前十名推荐任独立PI。研究方向主要聚焦RNA修饰调控疾病的发病机制及干预策略研究，综合运用线虫模式生物、类器官以及干细胞等多层次模型体系，系统解析疾病发生发展的分子与细胞机制。在研究过程中，依托细胞培养平台、生化分析平台及分子生物学平台，开展包括RNA修饰细胞功能检测、蛋白与代谢组学分析、基因调控与编辑等关键实验，以实现从基础机制到潜在治疗靶点的深入探索。以第一作者或共同第一作者身份将主要工作发表于Nature, Molecular Cell等期刊。目前正在十大正规买球的app排行榜筹建新的科研团队，课题组长期招聘对分子生物学、细胞生物学、表观转录组学、蛋白组学、分析化学等方向感兴趣的博士研究生、博士后和科研助理。简历发送至：daihui@ahmu.edu.cn

科研项目：

1.主持国家自然科学基金国家级人才计划青年项目1项

2.主持十大正规买球的app排行榜人才启动基金项目1项

论文著作：

1. Yuxiang Sun*,Hui Dai*, Xiaoxia Dai, Jiekai Yin, Yuxiang Cui, Xiaochuan Liu, Gwendolyn Gonzalez, Jun Yuan, Feng Tang, Nan Wang, Alexandra E. Perlegos, Nancy M. Bonini, X. William Yang, Weifeng Gu, Yinsheng Wang. m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration.Nature, 2023,580-587. (共同一作)IF=48.5

2. Yuxiang Sun, Zhouxian Li,Hui Dai, Yinsheng Wang. m⁶A modulates RAN translation from CAG repeat expansion RNA.Aggregate, 2025, 0:e70072.IF=13.7

3. Daniel A Chaves*,Hui Dai*, Lichao Li, James J Moresco, Myung Eun Oh, Darryl Conte Jr, John R Yates III, Craig C Mello, Weifeng Gu. The RNA phosphatase PIR-1 regulates endogenous small RNA pathways inC. elegans.Molecular Cell2021, 81, 1–12. (共同一作)IF=16.6

4.Hui Dai, Yun Liu, Jingjing Wang, Yaguang Nie, Yuxiang Sun, Mudi Wang, Dayan Wang, Zhen Yang, Lei Cheng, Juan Wang, Jian Weng, Qiuquan Wang, Fangyue Wang, Lijun Wu, Guoping Zhao, An Xu. Graphene oxide antagonizes the toxic response to arsenic via activation of protective autophagy and suppression of the arsenic-binding protein LEC-1 inCaenorhabditis elegans.Environmental Science: Nano, 2018, 1711-1728.IF=5.1

5.Hui Dai, Weifeng Gu. Strategies and best practice in cloning small RNAs. Gene technology 2020,9 (2)

6.Hui Dai, Weifeng Gu. Small RNA Plays Important Roles in Virus–Host Interactions.Viruses 2020,12 (11), 1271. IF=4.7

7. Lichao Li*,Hui Dai*, An-phong Nguyen, Rong Hai and Weifeng Gu. Influenza A virus utilizes noncanonical cap-snatching to diversify its mRNA/ncRNA.RNA 2020, 26 (9), 1170-1183.(共同一作) IF=3.9

8. Yuxiang Sun*,Hui Dai*, Shaopeng Chen, Ming Xu, Xuanyu Wang, Yajun Zhang, Shengmin Xu, An Xu, Jian Weng, Sijin Liu, Lijun Wu. Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions.Nanotoxicology 2018, 12 (2), 117-137.(共同一作)IF=5.9

9. Jingjing Wang*,Hui Dai*, Yaguang Nie, Mudi Wang, and An Xu. TiO2 nanoparticles enhanced bioaccumulation and toxicity of heavy metals in Caenorhabditis elegans via modification of local concentrations during the sedimentation process.Ecotoxicology and Environmental Safety.(共同一作) IF=6.2

10. Lichao Li, Hui Dai, An-phong Nguyen and Weifeng Gu. A convenient strategy to clone small RNA and mRNA for high-throughput sequencing.RNA 2020, 26 (2), 218-227.IF=3.9